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Institutional Review Board

IRB Reference Manual

Chapter Title
Chapter 1 The information previously found in Chapter 1 of the IRB Reference Manual has been incorporated into the IRB Policy and Procedure Manual.
Chapter 2 Chapter 2 has been incorporated into the IRB Policy and Procedure Manual as follows: Chapter IX includes information about the “No Human Subjects” and the “Not Research” designations; Chapter X includes information about Exempt Reviews; Chapter XI includes information about Expedited Reviews; Chapter XII includes information about Full Board Reviews; and Chapter XVI includes information about Emergency Use.
Chapter 3 Information regarding continuing review of research protocols can be found in the IRB Policy and Procedure Manual.
Chapter 4 Chapter 4 has been incorporated into the IRB Policy and Procedure Manual, Chapter VIII.K.
Chapter 5 Information regarding research subject and patient recruitment can be found in the IRB Policy and Procedure Manual.
Chapter 6 Information regarding special subject populations can be found in Chapter XIV of the IRB Policy and Procedure Manual
Chapter 7
Information related to submission of research studies through OSIRIS can be located at http://www.irb.pitt.edu/osiris/instructions/PI-Info.pdf.
Chapter 8 Information regarding the informed consent process and document - requirements and format has been incorporated into the Guidance section of the IRB website.
Chapter 9 Chapter 9 has been incorporated into the OSIRIS application under Investigator Responsibilities.
  Appendices
Appendix A IRB forms are accessible from the IRB Forms section of the IRB website.
Appendix B Information regarding the requirements and procedures for the emergency use of an unapproved investigational drug, biologic Or device has been incorporated into the Guidance section of the IRB website.
Appendix C "Off-Label" and investigational use of approved drugs and biologics guidance has been incorporated into the Guidance section of the IRB website.
Appendix D The Human Use Subcommittee, Radiation Safety Committee, And The Radioactive Drug Research Committee information has been incorporated into the Guidance section of the IRB website.
Appendix E Guidance regarding special considerations for the collection and use of tissue samples for genetic studies and other research purposes has been incorporated into the Guidance section of the IRB website.
Appendix F Investigational devices guidance has been incorporated into the Guidance section of the IRB website.
Appendix G Standard screening instruments not requiring submission with research protocols are listed in the Resources section of the IRB website.
Appendix H Sample consent forms can be found in the Model Consent Documents section of the IRB website.
Appendix I A glossary of lay terms can be found in the Resources section of the IRB website.
Appendix J Common abbreviations are listed in the Resources section of the IRB website.
Appendix K Some definitions of common terms can be found in the Resources section of the IRB website.
Appendix L Data and safety monitoring plans guidance has been incorporated into the Guidance section of the IRB website.
Appendix M Information about obtaining written informed consent of family members when research involves the collection of their private info has been incorporated into the Guidance section of the IRB website.
Appendix N Humanitarian device exemptions guidance has been incorporated into the Guidance section of the IRB website.
Appendix O The Research Participant Information Sheet can be found in the Resources section of the IRB website.
Appendix P Coordinating center guidance has been incorporated into the Guidance section of the IRB website.
Appendix Q Information related to conflict of interest can be found at http://www.coi.pitt.edu/.