Investigators involved in the conduct of human subject research that falls under the authority of the HRPO will be provided with instructions and guidelines for the submission of research studies and informed consent documents for IRB review and approval. Specific instructions are found on the PittPRO webpage. Refer to the Help Center, Library and Sandbox. Studies that are approved through OSIRIS will follow the instructions found on the OSIRIS webpage as well as in help text located throughout the OSIRIS system. The following are general procedures for the IRB in processing all IRB submissions.